Gut microbiome · metagenomic sequencing of stool samples
Diversity, short-chain fatty acid producers and weight management markers
Biological drift is the gradual shift in your cells, genes and metabolism as you age, showing up as weight that won't budge, hormones in flux, brain fog, low energy and a body that feels older than it should.
A single test shows this drift. Two tests shows its direction. Testing three or more times shows where it's heading, giving you time to change course before symptoms become harder to reverse. The best part? Every test happens at home.
A second test shows whether your biology is heading the right way, often before symptoms like brain fog or low mood become obvious.
Your first test shows exactly where your weight, hormones, energy and gut function stand today, before you change anything.
Three or more tests let vivaSIM model your trajectory, showing what's likely next and what to change now to shift it.
Every test reads combined weight, hormones, gut function and energy signals, so your baseline, direction and forecast tell one connected story.
Select a symptom to see the biology behind it.
“I've done all the diets but I still can't keep the weight off.”
The number on the scale shows direction, not composition: it cannot tell you whether you are losing fat or muscle. Sleep is one input, and one week of restricted sleep reduced insulin sensitivity in healthy men.[1] An under-active thyroid is a recognised cause of weight gain on an unchanged diet,[2] and through the menopause transition fat mass tends to rise while lean mass falls.[3]
Weight is often the first illustration of underlying biological drift that you notice, not the only one. Insulin sensitivity and muscle mass tend to change quietly, and a scale cannot show either.
Test once to discover where you are. Test again to track which way you are moving.
If you take a prescribed weight-loss medicine, never change or stop it on the basis of a test result without speaking to your prescribing doctor. If eating or weight is causing you distress, the Butterfly Foundation helpline is 1800 33 4673.
Diversity, short-chain fatty acid producers and weight management markers
Carbohydrate, fatty acid and energy metabolism
Metabolism, physical activity and sleep scores, with your estimated energy requirement
Thyroid function, HbA1c, fasting insulin and sex hormones are GP blood tests. The full guide explains which to ask for.
Weight Management is always more than just one thing. Find out more about the six systems that influence weight management, how testing can help you make the right decisions, and take the Weight Management Quiz.
References:
Standard testing will tell you an issue exists but it doesn't tell you why. Our proprietary tri-layer testing protocol decodes your gut microbiome, metabolic health and lifestyle information at a cellular level. It provides you the context behind your sleep issues, brain fog, weight gain, energy slumps and hormone changes - your Biological Drift. The best bit? You do all your testing at home.
Your gut microbiome is a complex community of trillions of microorganisms influencing digestion, metabolism, cognitive, mood and immune function and general energy.
Metabolism determines how efficiently your gut converts food into energy, amino and fatty acids, and how efficiently they are used by your body in all of its processes.
When, what and how much you eat, how often you exercise, past and present health and medications, all further contextualise your biological data.
Tracking your biology over time helps you see your Biological Drift to optimise your digestion, sleep, immunity, energy levels, cognitive function, hormones and longevity
Our biology and lifestyles are all unique and change over time. Our once-off tests and scheduled testing membership plans provide you a snapshot of where your biology is today and where it's heading, to you help you make the appropriate decisions for your future health.
Gut microbiota significantly influences your skin, hair, nails, brain function and menopause symptoms.
Reducing cardiovascular risk, brain fog, fatigue, and joint pain are all linked to a healthy gut.
Hear how vivaBALANCE has helped others transform their gut health, energy levels, and daily wellbeing powered by personalised, science-backed nutrition.
Stay informed with our curated selection of the latest studies and expert insights in decoding your own biometric data to track your biological drift to improve your healthspan.
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Every numbered claim on this page links to a record in PubMed, the US National Library of Medicine's index of biomedical literature.
Hills RD, Pontefract BA, Mishcon HR, Black CA, Sutton SC, Theberge CR. Gut Microbiome: Profound Implications for Diet and Disease. Nutrients. 2019;11(7):1613. PMID: 31315227
Rathore K, Shukla N, Naik S, Sambhav K, Dange K, Bhuyan D, Haq QMI. The Bidirectional Relationship Between the Gut Microbiome and Mental Health: A Comprehensive Review. Cureus. 2025;17(3):e80810. PMID: 40255763
Cryan JF, O'Riordan KJ, Cowan CSM, et al. The Microbiota-Gut-Brain Axis. Physiol Rev. 2019;99(4):1877-2013. PMID: 31460832
Baker JM, Al-Nakkash L, Herbst-Kralovetz MM. Estrogen-gut microbiome axis: Physiological and clinical implications. Maturitas. 2017;103:45-53. PMID: 28778332
Zhao Y, Yu C, Zhang J, Yao Q, Zhu X, Zhou X. The gut-skin axis: Emerging insights in understanding and treating skin diseases through gut microbiome modulation (Review). Int J Mol Med. 2025;56(6):210. PMID: 41041846
Liu Z, Liu X. Gut microbiome, metabolome and alopecia areata. Front Microbiol. 2023;14:1281660. doi:10.3389/fmicb.2023.1281660
Zhang S, Li J, Li L, Yuan X. Gut microbiota on cardiovascular diseases: a mini review on current evidence. Front Microbiol. 2025. doi:10.3389/fmicb.2025.1690411
Sánchez Romero EA, Meléndez Oliva E, Alonso Pérez JL, Martín Pérez S, Turroni S, Marchese L, Villafañe JH. Relationship between the Gut Microbiome and Osteoarthritis Pain: Review of the Literature. Nutrients. 2021;13(3):716. PMID: 33668236
Asadi A, Shadab Mehr N, Mohamadi MH, Shokri F, Heidary M, Sadeghifard N, Khoshnood S. Obesity and gut-microbiota-brain axis: A narrative review. J Clin Lab Anal. 2022;36(5):e24420. PMID: 35421277
Oh HSH, Rutledge J, Nie D, et al. Organ aging signatures in the plasma proteome track health and disease. Nature. 2023;624(7990):164-172. PMID: 38057571